Induction of mania with serotonin reuptake inhibitors.

@article{Howland1996InductionOM,
  title={Induction of mania with serotonin reuptake inhibitors.},
  author={Robert H. Howland},
  journal={Journal of clinical psychopharmacology},
  year={1996},
  volume={16 6},
  pages={425-7}
}
Serotonin reuptake inhibitors (SRIs) are now considered the first-line treatment for depression, but they have not been well studied in bipolar disorder. Recently, some authors have recommended that patients at risk for antidepressant-induced mania be treated with SRIs rather than tricyclic antidepressants (TCAs). Clinical information about 11 patients who developed mania during treatment with SRIs is described. These patients were found to have personal or family histories of hypomania or… CONTINUE READING
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