Induction of mRNA for chemokines and chemokine receptors by prostaglandin F2α is dependent upon stage of the porcine corpus luteum and intraluteal progesterone.

@article{Luo2011InductionOM,
  title={Induction of mRNA for chemokines and chemokine receptors by prostaglandin F2α is dependent upon stage of the porcine corpus luteum and intraluteal progesterone.},
  author={Wenxiang Luo and Francisco Javier Parra D{\'i}az and Milo C Wiltbank},
  journal={Endocrinology},
  year={2011},
  volume={152 7},
  pages={
          2797-805
        }
}
This study tested the hypotheses that prostaglandin (PG) F(2α) increases expression of genes related to recruitment of leukocytes in mature but not early corpus luteum (CL) and that insensitivity to PGF(2α) action in early CL is dependent on high intraluteal progesterone (P4) concentrations. Experiment 1 examined early (0.5 h) and late (10 h) in vivo effects of PGF(2α) on mature (d 17 of pseudopregnancy) and early (d 9) porcine CL. Real-time PCR was used to measure mRNA for chemokines (IL8… CONTINUE READING

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