Induction of lymphopenia and inhibition of T cell function during acute infection of swine with foot and mouth disease virus (FMDV).

@article{Bautista2003InductionOL,
  title={Induction of lymphopenia and inhibition of T cell function during acute infection of swine with foot and mouth disease virus (FMDV).},
  author={Elida M. Bautista and Geoffrey S. Ferman and William T. Golde},
  journal={Veterinary immunology and immunopathology},
  year={2003},
  volume={92 1-2},
  pages={61-73}
}
Foot and mouth disease virus (FMDV) is a picornavirus that causes an acute vesicular disease of cloven-hoofed animals. This virus continues to be a threat to livestock worldwide with outbreaks causing severe economic losses. The present study shows an analysis of immune system phenotype and function during the acute phase of FMDV infection in swine. In the first days of infection, a significant lymphopenia is observed that involves all T cell subsets, CD4(+), CD8(+), and CD4(+)/CD8(+). This… CONTINUE READING
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