Induction of lung fibrosis in the mouse by intratracheal instillation of fluorescein isothiocyanate is not T-cell-dependent.

@article{Christensen1999InductionOL,
  title={Induction of lung fibrosis in the mouse by intratracheal instillation of fluorescein isothiocyanate is not T-cell-dependent.},
  author={Paul Christensen and Russell Goodman and Laura Pastoriza and Bethany B Moore and Galen B. Toews},
  journal={The American journal of pathology},
  year={1999},
  volume={155 5},
  pages={1773-9}
}
Pulmonary fibrosis is the pathological result of a diverse group of insults. Common features of this group of diseases include chronic inflammation and immune cell activation. The pathogenesis of pulmonary fibrosis is not well defined and the prognosis is poor, highlighting the need for good animal models to elucidate the cellular and molecular events that lead to pulmonary fibrosis. This paper provides insight on a newly described model of pulmonary fibrosis using a single intratracheal… CONTINUE READING
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