Induction of keratinocyte growth factor expression is reduced and delayed during wound healing in the genetically diabetic mouse.

@article{Werner1994InductionOK,
  title={Induction of keratinocyte growth factor expression is reduced and delayed during wound healing in the genetically diabetic mouse.},
  author={Susanne Werner and M P Breeden and G. H{\"u}bner and David G. Greenhalgh and Michael Thornton Longaker},
  journal={The Journal of investigative dermatology},
  year={1994},
  volume={103 4},
  pages={469-73}
}
We have recently demonstrated induction of expression of several members of the fibroblast growth factor family during wound healing, particularly for keratinocyte growth factor, which was more than 150-fold induced within 24 h after injury. To assess whether wound-healing disorders are associated with a defect in fibroblast growth factor regulation, we have now investigated the expression of these mitogens as well as their receptors in normal and wounded skin of genetically diabetic db/db mice… CONTINUE READING

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