Induction of infertility in adult male bonnet monkeys by immunization with phage-expressed peptides of the extracellular domain of FSH receptor.

@article{Rao2004InductionOI,
  title={Induction of infertility in adult male bonnet monkeys by immunization with phage-expressed peptides of the extracellular domain of FSH receptor.},
  author={A. Jagannadha Rao and Subbaraya G. Ramachandra and Vishwajith Ramesh and Laurence Couture and Latifa Abdennebi and Roland Salesse and Jean Jacques Remy},
  journal={Reproductive biomedicine online},
  year={2004},
  volume={8 4},
  pages={
          385-91
        }
}
Active immunization of proven fertile adult male bonnet monkeys (Macaca radiata) with phage-expressed follicle-stimulating hormone receptor (FSHR)-specific peptides from the extracellular domain resulted in a progressive drop in sperm count with all animals becoming azoospermic by day 100. However, serum testosterone concentrations were unaltered during the… CONTINUE READING