Induction of immune reaction against rat embryonal carcinoma by activation of viral genome.

@article{Sobis1980InductionOI,
  title={Induction of immune reaction against rat embryonal carcinoma by activation of viral genome.},
  author={H. Sobis and Lil van Hove and Hubertine Heremans and M DeLey and Alfons Billiau and Michel Vandeputte},
  journal={International journal of cancer},
  year={1980},
  volume={26 1},
  pages={93-9}
}
A cell line (F3/1) derived from a rat embryonal carcinoma, originally induced in fetectomized rats injected with MSV, was found to be essentially non-immunogenic in a syngeneic host; the cells did not produce C-type virions. The MSV genome could be rescued by superinfection of F3/1 cells with endogenous C-type mouse virus and the cells were converted in a… CONTINUE READING