Induction of immediate-early genes c-fos and Zif268 in the subnucleus oralis by noxious dental stimulation

@article{He1998InductionOI,
  title={Induction of immediate-early genes c-fos and Zif268 in the subnucleus oralis by noxious dental stimulation},
  author={Yuehua He and Makoto Funahashi and Hiroyuki Ichikawa and Tomosada Sugimoto},
  journal={Neuroscience Research},
  year={1998},
  volume={31}
}
c-fos and zif268 expression was assessed by immunocytochemistry for their protein products in the senson’ trigeminal nuclear complex 2 hours after noxious mechanical stimulation of the mandibular incisor pulp of pentobarbital-anesthetized rats. A cavity reaching the necrotic part of the pulp was prepared and an endodontic reamer was inserted 3-4 times into the vital part of the pulp. The trigeminal complex of unstimulated rats yielded no c-Fos and weak background Zif268-immunoreactivities. Pulp… CONTINUE READING
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