Induction of human umbilical cord blood-derived stem cells with embryonic stem cell phenotypes into insulin producing islet-like structure.

@article{Sun2007InductionOH,
  title={Induction of human umbilical cord blood-derived stem cells with embryonic stem cell phenotypes into insulin producing islet-like structure.},
  author={Bo kyung Sun and Kyung-Hwan Roh and Saerom Lee and Yat Tim Anita Lee and Kun Young Kang},
  journal={Biochemical and biophysical research communications},
  year={2007},
  volume={354 4},
  pages={
          919-23
        }
}
Success in islet-transplantation-based therapies for type I diabetes, coupled with a worldwide shortage of transplant-ready islets, has motivated efforts to develop renewable sources of islet-replacement tissue. Embryonic stem cells (ESCs) have been successfully induced into insulin producing islet-like structure in several studies. However, the source of the ESCs has presented ethical and technical concerns. Here, we isolated a population of stem cells from human cord blood (UCB), which… CONTINUE READING
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