Induction of human monocyte to macrophage maturation in vitro by 1,25-dihydroxyvitamin D3.

@article{Kreutz1990InductionOH,
  title={Induction of human monocyte to macrophage maturation in vitro by 1,25-dihydroxyvitamin D3.},
  author={Marina P. Kreutz and Reinhard Andreesen},
  journal={Blood},
  year={1990},
  volume={76 12},
  pages={
          2457-61
        }
}
Cells of the mononuclear phagocyte system arise from circulating blood monocytes (MO) that undergo further maturation on leaving the vasculature and migration into the various tissues and body cavities. This terminal differentiation step is also observed in vitro when blood MO are cultured in the presence of serum. Yet, the inducing signals present in serum are not defined. We have established primary cultures from elutriation-purified blood MO and found that the active metabolite of vitamin D3… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 34 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 37 REFERENCES

Activation of human monocyte-derived macrophages cultured on teflon: Response to interferon-gamma during terminal maturation in vitro

  • R Andreesen, W Gadd S. Brugger, GW Lohr, RC Atkins
  • Immunobiology 177:186,
  • 1988

Similar Papers

Loading similar papers…