Induction of host defence responses by Drosophila C virus.

  title={Induction of host defence responses by Drosophila C virus.},
  author={Lauren M. Hedges and Karyn N Johnson},
  journal={The Journal of general virology},
  volume={89 Pt 6},
Insect responses that are specific for virus infection have been investigated using the genetically tractable Drosophila melanogaster. Most studies focus on interactions with Drosophila C virus (DCV), which is a member of the family Dicistroviridae. DCV is a non-enveloped, T=3 icosahedral virus with a positive-sense RNA genome. It was demonstrated recently that several genes controlled by the Jak-STAT pathway are specifically upregulated upon DCV infection. To investigate the virus factors that… CONTINUE READING