Induction of heat shock and stress proteins in promastigotes of three Leishmania species.

@article{Lawrence1985InductionOH,
  title={Induction of heat shock and stress proteins in promastigotes of three Leishmania species.},
  author={Françoise Lawrence and Malka Robert-Gero},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1985},
  volume={82 13},
  pages={4414-7}
}
The induction of heat shock proteins in three species of Leishmania, L. tropica, L. enrietti, and L. donovani is reported. When cultures of promastigotes are shifted from 26 degrees C to 37 degrees C or 40 degrees C, the synthesis of proteins with apparent molecular weights of 88,000, 74,000, and 54,000 is stimulated. Actinomycin D added just prior to the shift prevented the appearance of these proteins but had no effect when present 30 min after the transfer onward, suggesting that the… CONTINUE READING

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