Induction of germ-line anti-alpha 1-3 dextran antibody responses in mice by members of the Enterobacteriaceae family.

@article{Kearney1985InductionOG,
  title={Induction of germ-line anti-alpha 1-3 dextran antibody responses in mice by members of the Enterobacteriaceae family.},
  author={John F Kearney and Madeline McCarthy and R C Stohrer and William H. Benjamin and David E. Briles},
  journal={Journal of immunology},
  year={1985},
  volume={135 5},
  pages={3468-72}
}
A large panel of enteric organisms was screened for agglutination with a panel of lambda monoclonal antibodies of different heavy chain isotypes specific for alpha 1-3 dextran (DEX). Two strains were initially isolated that were bound by most of the anti-DEX antibodies. One organism, Enterobacter cloacae strain MK7, which was characterized in detail, induced a typical lambda anti-DEX response in Igh-Ca mice that had a fine idiotope profile comparable with that induced by purified B1355S dextran… CONTINUE READING