Induction of follicular development by direct single injection of vascular endothelial growth factor gene fragments into the ovary of miniature gilts.

@article{Shimizu2003InductionOF,
  title={Induction of follicular development by direct single injection of vascular endothelial growth factor gene fragments into the ovary of miniature gilts.},
  author={Takashi Shimizu and Jin-Yi Jiang and Koji Iijima and Kanako Miyabayashi and Yoshinori Ogawa and Hiroshi Sasada and Eimei Sato},
  journal={Biology of reproduction},
  year={2003},
  volume={69 4},
  pages={1388-93}
}
Perifollicular angiogenesis is closely associated with ovarian follicular development. To investigate whether additional induction of perifollicular angiogenesis would support subsequent follicular development, we directly injected vascular endothelial growth factor (VEGF) gene fragments into the ovaries of miniature gilts, followed by gonadotroph treatment to stimulate follicle growth. In addition, to confirm extraexpression of the VEGF gene after injection, we assessed the expression of two… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

Similar Papers

Loading similar papers…