Induction of fetal hemoglobin in sickle cell disease.

@article{Bunn1999InductionOF,
  title={Induction of fetal hemoglobin in sickle cell disease.},
  author={Helen. Bunn},
  journal={Blood},
  year={1999},
  volume={93 6},
  pages={
          1787-9
        }
}
on the induction of fetal hemoglobin (Hb F) by pulse butyrate. This study is a solid addition to the recent and gratifying momentum in the development of effective therapy for sickle cell disease. Underlying this report is a series of novel and convincing in vivo studies extending from model systems in the chicken, 2 sheep, 3 and baboons 4-6 to observations on babies of diabetic mothers 7 and on patients with metabolic disorders8 and hemoglobinopathies, 9,10all indicating that butyrates and… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 16 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 24 REFERENCES

Similar Papers

Loading similar papers…