Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors

@article{Vijayakumar2012InductionOF,
  title={Induction of fatty acid oxidation resists weight gain, ameliorates hepatic steatosis and reduces cardiometabolic risk factors},
  author={R. S. Vijayakumar and Y. Lin and K-S Shia and Y-N Yeh and W-P Hsieh and W-C Hsiao and C-P Chang and Y-S Chao and M. Hung},
  journal={International Journal of Obesity},
  year={2012},
  volume={36},
  pages={999-1006}
}
  • R. S. Vijayakumar, Y. Lin, +6 authors M. Hung
  • Published 2012
  • Chemistry, Medicine
  • International Journal of Obesity
  • Objective:Fatty acid oxidation has been implicated in amelioration of obesity by burning off excessive accumulated lipid. BPR697, a peripheral cannabinoid receptor 1 (CB1) antagonist, elevated fat oxidation without added energy expenditure. Its impact on food intake, body weight changes and metabolic alterations were examined in rats fed standard chow and in diet-induced obesity (DIO) mice.Materials and methods:CB1 agonist-induced hypothermia and analgesia responses were measured to examine the… CONTINUE READING
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