Induction of erythroid differentiation in murine virus infected eythroleukemia cells by highly polar compounds.

@article{Tanaka1975InductionOE,
  title={Induction of erythroid differentiation in murine virus infected eythroleukemia cells by highly polar compounds.},
  author={Masao Tanaka and Joseph Levy and Masaki Terada and Ronald Breslow and Richard A. Rifkind and Paul A. Marks},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1975},
  volume={72 3},
  pages={1003-6}
}
Murine-virus-infected erythroleukemia cells cultured in a medium with dimethylsulfoxide or N,N-dimethylformamide are induced to differentiate to erythroid cells. A number of highly polar compounds have a similar effect in inducing erythroid differentiation of the virus-infected cells, as assayed by the appearance of hemoglobin. These compounds are 1-methyl-1-2-piperidone, N,N-dimethylacetamide, N-methylpyrrolidinone, N-methylacetamide, 2-pyrrolidinone, propionamide, pyridine-N-oxide, piperidone… CONTINUE READING

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