• DOI:10.1016/0890-6238(95)00004-T
Corpus ID: 23904208

Induction of endometriosis in mice: a new model sensitive to estrogen.

@article{Cummings1995InductionOE,
  title={Induction of endometriosis in mice: a new model sensitive to estrogen.},
  author={A. Cummings and J. L. Metcalf},
  journal={Reproductive toxicology},
  year={1995},
  volume={9 3},
  pages={
          233-8
        }
}

A. Cummings, J. L. Metcalf

Published 1995

Medicine

Reproductive toxicology

Endometriosis consists of the growth of endometrial tissue outside the uterus. A rat model of endometriosis is available to evaluate the potential for environmental chemicals to promote the disease but may be relatively insensitive for the evaluation of the hazard of certain compounds. Our objective, which was to develop a mouse model for endometriosis, was based on (a) the promotion of endometriosis in primates by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD), (b) the apparent relationship… CONTINUE READING

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