Induction of differentiation rescues HL-60 cells from Rana catesbeiana ribonuclease-induced cell death.

Abstract

Rana catesbeiana ribonuclease (RC-RNase) exerted strong anti-tumor activity and its cytotoxicity was shown to correlate with differentiation stages of three different hepatoma cell lines. In this study, we demonstrate different RC-RNase cytotoxicity in undifferentiated HL-60 cells and in those that had been induced to differentiate by retinoic acid or… (More)

Topics

Cite this paper

@article{Wei2002InductionOD, title={Induction of differentiation rescues HL-60 cells from Rana catesbeiana ribonuclease-induced cell death.}, author={Chyou Wei Wei and Chih Chi Hu and Chih Hang Anthony Tang and Ming Chieh Lee and Jaang Jiun Wang}, journal={FEBS letters}, year={2002}, volume={531 3}, pages={421-6} }