Induction of dendritic cell maturation by β-glucan isolated from Sparassis crispa.

@article{Kim2010InductionOD,
  title={Induction of dendritic cell maturation by $\beta$-glucan isolated from Sparassis crispa.},
  author={Hyung Sook Kim and Jee Youn Kim and Hwa Sun Ryu and Hyuk-Gu Park and Yong Ok Kim and Jong Soon Kang and Hwan-Mook Kim and Jin Tae Hong and Youngsoo Kim and Sang Bae Han},
  journal={International immunopharmacology},
  year={2010},
  volume={10 10},
  pages={
          1284-94
        }
}
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Activation of macrophages by polysaccharide isolated from Paecilomyces cicadae through toll-like receptor 4.
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Proteoglycan isolated from Phellinus linteus induces toll-like receptors 2- and 4-mediated maturation of murine dendritic cells via activation of ERK, p38, and NF-kappaB.
TLDR
It is demonstrated that PL stimulation could induce the phenotypic and functional maturation of DC via TLR2 and/or TLR4 mediated-NF-kappaB, ERK and p38 MAPK signal pathways and Toll-like receptors may be the receptor(s) of PL.
IFN-γ Induction by SCG, 1,3-β-D-Glucan from Sparassis crispa, in DBA/2 Mice In Vitro
TLDR
Interferon-γ (IFN-γ) induction by SCG from splenocytes in DBA/2 mice in vitro was examined and it was suggested that soluble factors and cell-cell contact med...
Highly expressed dectin-1 on bone marrow-derived dendritic cells regulates the sensitivity to beta-glucan in DBA/2 mice.
TLDR
The results suggest that the BMDCs from DBA/2 mice are highly sensitive to the induction of cytokine production by SCG in vitro, and that this sensitivity is related to the expression level of dectin-1.
Water extract of Cordyceps militaris enhances maturation of murine bone marrow-derived dendritic cells in vitro.
TLDR
Water extract of Cordyceps militaris induces the phenotypic and functional maturation of dendritic cells (DC) and is shown to promote the cytotoxicity of specific-cytotoxic T lymphocytes induced by DC which were pulsed with P815 tumor-lysate during the stage of antigen presentation.
Enhanced Cytokine Synthesis of Leukocytes by a β‐Glucan Preparation, SCG, Extracted from a Medicinal Mushroom, Sparassis crispa
TLDR
SCG was observed to have the capacity to activate human leukocytes and related immune system in an in vitro human system.
Effect of SCG, 1,3-beta-D-glucan from Sparassis crispa on the hematopoietic response in cyclophosphamide induced leukopenic mice.
TLDR
The possibility that IL-6 might be a key cytokine for the enhanced hematopoietic response by SCG is suggested.
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