Induction of cytotoxicity by photoexcited TiO2 particles.

  title={Induction of cytotoxicity by photoexcited TiO2 particles.},
  author={Ru-xiu Cai and Yasuo Kubota and Taro Shuin and Hidekazu Sakai and Ken Hashimoto and Akira Fujishima},
  journal={Cancer research},
  volume={52 8},
Photoexcited TiO2 particles can drive various chemical reactions due to their strong oxidizing and reducing ability. To investigate the possible use of this effect for cancer treatment, the antitumor activity of photoexcited TiO2 particles was studied in vitro and in vivo. HeLa cells cultured in vitro were completely killed in the presence of TiO2 (50 micrograms/ml) with 10-min UV irradiation by a 500-W-Hg lamp. In contrast, very little cell death was observed from TiO2 treatment without UV… CONTINUE READING

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