Induction of cytokine gene expression in human thyroid epithelial cells irradiated with HZE particles (iron ions).

@article{Sanzari2009InductionOC,
  title={Induction of cytokine gene expression in human thyroid epithelial cells irradiated with HZE particles (iron ions).},
  author={Jenine K. Sanzari and Manunya Nuth and Ann R. Kennedy},
  journal={Radiation research},
  year={2009},
  volume={172 4},
  pages={437-43}
}
Gene expression profiles were examined using cDNA microarray technology in human thyroid epithelial (Htori-3) cells exposed to a low, non-toxic dose (10 cGy) of radiation from HZE particles in the form of iron ions in the absence or presence of selenomethionine (SeM). A total of 215 genes were differentially regulated 2 h after exposure to a 10-cGy dose of iron-ion radiation. In the microarray analysis, SeM had profound effects on the radiation-induced expression of several specific genes… CONTINUE READING

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