Induction of cytochromes P-450 in pancreatic disease: consequence, coincidence or cause?

Abstract

We have examined the pharmacokinetics of antipyrine and of theophylline--validated probes for cytochromes P-450 activities--in a series of patients with pancreatic disease. The half-life of each drug was significantly lower, and its clearance faster, in patients than in controls and this pattern was detected in the subgroups with acute pancreatitis (6… (More)

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Cite this paper

@article{Acheson1985InductionOC, title={Induction of cytochromes P-450 in pancreatic disease: consequence, coincidence or cause?}, author={David W. K. Acheson and Peter G Rose and James Brian Houston and Joan Marie Braganza}, journal={Clinica chimica acta; international journal of clinical chemistry}, year={1985}, volume={153 2}, pages={73-84} }