Induction of cellular contractions in the human melanoma cell line SK-mel 28 after muscarinic cholinergic stimulation

@article{Sailer2000InductionOC,
  title={Induction of cellular contractions in the human melanoma cell line SK-mel 28 after muscarinic cholinergic stimulation},
  author={Michael Sailer and Matthias Oppitz and Ulrich Drews},
  journal={Anatomy and Embryology},
  year={2000},
  volume={201},
  pages={27-37}
}
In a previous immunohistochemical study we observed muscarinic acetylcholine receptors in primary and metastatic human melanomas, which were not present in normal skin melanocytes. In the present study we demonstrated the endogenous expression of muscarinic receptors, of choline acetyltransferase and of cholinesterase activity in the human melanoma cell line SK-mel 28. We tested the effect of muscarinic agonists on cellular movements of the melanoma cells in a perfusion chamber by digital video… CONTINUE READING

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