Induction of cell cycle arrest by increasing GTP-RhoA levels via Taxol-induced microtubule polymerization in renal cell carcinoma

@inproceedings{Ren2017InductionOC,
  title={Induction of cell cycle arrest by increasing GTP-RhoA levels via Taxol-induced microtubule polymerization in renal cell carcinoma},
  author={Yu Hu Ren and Xue Wang and Zhongguan Lou and Shuaishuai Huang and Haihui Zhuang and Yuduo Wang and Guobin Weng and Ping Wang},
  booktitle={Molecular medicine reports},
  year={2017}
}
Renal cell carcinoma (RCC) is the most common neoplasm of the kidney in adults, accounting for ~3% of adult malignancies. Understanding the underlying mechanism of RCC tumorigenesis is necessary to improve patient survival. The present study revealed that Taxol‑induced microtubule (MT) polymerization causes cell cycle arrest and an increase in guanosine… CONTINUE READING