Induction of cardiac FABP gene expression by long chain fatty acids in cultured rat muscle cells

@article{Chang2001InductionOC,
  title={Induction of cardiac FABP gene expression by long chain fatty acids in cultured rat muscle cells},
  author={Weihua Chang and Jutta Rickers-Haunerland and Norbert H. Haunerland},
  journal={Molecular and Cellular Biochemistry},
  year={2001},
  volume={221},
  pages={127-132}
}
The induction of cardiac FABP expression by long‐chain fatty acids was measured in cultured rat myoblasts, myotubes and adult cardiomyocytes. With quantitative RT‐PCR techniques, the primary transcription product of the FABP gene and the mature mRNA were measured. Incubations of 30 min resulted in a larger than 2‐fold increase of the primary transcript in all cells, and FABP mRNA more than doubled in myoblasts and cardiomyocytes after 10 h of fatty acid exposure. The results demonstrate that… CONTINUE READING
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