Induction of autophagy by B cell antigen receptor stimulation and its inhibition by costimulation.

Abstract

Autophagy is a major pathway for degradation of cytoplasmic components, and is induced by some apoptotic stimuli mostly in cancer cells under the condition in which apoptosis is blocked. Ligation of the B cell antigen receptor (BCR) induces apoptosis and plays a crucial role in self-tolerance. However, whether BCR ligation induces autophagy is not clear… (More)
DOI: 10.1016/j.bbrc.2008.07.013

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Cite this paper

@article{Watanabe2008InductionOA, title={Induction of autophagy by B cell antigen receptor stimulation and its inhibition by costimulation.}, author={Kozo Watanabe and Shizuko Ichinose and Koji Hayashizaki and Takeshi Tsubata}, journal={Biochemical and biophysical research communications}, year={2008}, volume={374 2}, pages={274-81} }