Induction of apoptotic cell death by Pharbitis nil extract in HER2-overexpressing MCF-7 cells.

@article{Ju2011InductionOA,
  title={Induction of apoptotic cell death by Pharbitis nil extract in HER2-overexpressing MCF-7 cells.},
  author={Ji-hyun Ju and Min Jeong Jeon and WonSeok Yang and Kyung-min Lee and H Seo and Incheol Shin},
  journal={Journal of ethnopharmacology},
  year={2011},
  volume={133 1},
  pages={126-31}
}
AIM OF THE STUDY We performed this study to investigate the anti-cancer activity of Pharbitis nil (PN) ethanol extract which has been used for herbal medicinal treatment against diseases in East Asia. MATERIALS AND METHODS We analyzed the effects of PN extract on proliferation of breast cancer cell lines, MCF-7 control vector (vec) and MCF-7 human epidermal growth factor receptor 2 (HER2) cells engineered to overexpress oncogenic HER2 via retroviral infection. We performed the proliferation… CONTINUE READING