Corpus ID: 15522803

Induction of apoptotic cell death and in vivo growth inhibition of human cancer cells by a saturated branched-chain fatty acid, 13-methyltetradecanoic acid.

@article{Yang2000InductionOA,
  title={Induction of apoptotic cell death and in vivo growth inhibition of human cancer cells by a saturated branched-chain fatty acid, 13-methyltetradecanoic acid.},
  author={Z. Yang and S. Liu and X. Chen and H. Chen and M. Huang and J. Zheng},
  journal={Cancer research},
  year={2000},
  volume={60 3},
  pages={
          505-9
        }
}
  • Z. Yang, S. Liu, +3 authors J. Zheng
  • Published 2000
  • Biology, Medicine
  • Cancer research
  • A saturated branched-chain fatty acid, 13-methyltetradecanoic acid (13-MTD), was purified from a soy fermentation product, which was used by many cancer patients as a treatment supplement. Our preliminary study indicated that 13-MTD could induce cell death in human cancer cell lines K-562, MCF7, DU 145, NCI-SNU-1, SNU-423, NCI-H1688, BxPC3, and HCT 116. The ID50 dosage of 13-MTD for these tumor cells ranged from 10 to 25 microg/ml. Further investigation revealed that 13-MTD caused tumor cell… CONTINUE READING
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