Induction of apoptosis pathways in several cell lines following exposure to the marine algal toxin azaspiracid.

@article{Twiner2012InductionOA,
  title={Induction of apoptosis pathways in several cell lines following exposure to the marine algal toxin azaspiracid.},
  author={Michael J. Twiner and Joshua C Hanagriff and Suzanne Butler and Ahmed K Madhkoor and Gregory J. Doucette},
  journal={Chemical research in toxicology},
  year={2012},
  volume={25 7},
  pages={1493-501}
}
Azaspiracids (AZAs) are polyether marine dinoflagellate toxins that accumulate in shellfish and represent an emerging human health risk. Although there have been no deaths associated with the AZA toxins, humans exposed to AZAs experience severe gastrointestinal symptoms. This toxin class has been shown to be highly cytotoxic, a teratogen to developing fish, and a possible carcinogen in mice. Just recently, the AZAs have been shown to be potassium channel inhibitors. This report employed… CONTINUE READING

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