Induction of apoptosis in ischemia-reperfusion model of mouse kidney: possible involvement of Fas.

@article{Nogae1998InductionOA,
  title={Induction of apoptosis in ischemia-reperfusion model of mouse kidney: possible involvement of Fas.},
  author={Shoji Nogae and Masanobu Miyazaki and Naoto Kobayashi and Takashi Saito and Katsushige Abe and Hideyuki Saito and Paul K. Nakane and Yoshinobu Nakanishi and Takehiko Koji},
  journal={Journal of the American Society of Nephrology : JASN},
  year={1998},
  volume={9 4},
  pages={620-31}
}
Although ischemia-reperfusion of mouse kidney is known to cause severe renal failure due to tubular cell death, the exact cellular mechanism responsible for this phenomenon is not clear. To investigate the spatial and temporal development of renal cell death and the role of Fas/APO-1/CD95 (Fas) in this process, the left renal vessels were occluded in a group of mice for 30, 60, or 120 min followed by reperfusion for 24 h (n = 4 for each group). Analysis of the isolated DNA in agarose-gel… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 58 extracted citations

Cell death induced by acute renal injury: a perspective on the contributions of apoptosis and necrosis.

American journal of physiology. Renal physiology • 2003
View 20 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…