Induction of apoptosis in human leukemia cells by black tea and its polyphenol theaflavin.

@article{Kundu2005InductionOA,
  title={Induction of apoptosis in human leukemia cells by black tea and its polyphenol theaflavin.},
  author={Trina Kundu and Subhabrata Dey and M. Roy and M. Siddiqi and R. K. Bhattacharya},
  journal={Cancer letters},
  year={2005},
  volume={230 1},
  pages={
          111-21
        }
}
Treatment of human leukemic cell lines HL-60 and K-562 with extracts of green and black tea and their polyphenols epigallocatechin gallate and theaflavins, respectively, showed a dose dependent inhibition of growth as a result of cytotoxicity and suppression of cell proliferation. Based on the IC50 values obtained from cytotoxicity data it was clearly evident that black tea was as efficient as green tea. Analysis of polyphenol contents of tea extracts revealed that not only epigallocatechin… Expand
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