Induction of apoptosis in human hepatoma SMMC-7721 cells by solamargine from Solanum nigrum L.

@article{Ding2012InductionOA,
  title={Induction of apoptosis in human hepatoma SMMC-7721 cells by solamargine from Solanum nigrum L.},
  author={Xia Ding and Fang-shi Zhu and Min Li and Si-Guo Gao},
  journal={Journal of ethnopharmacology},
  year={2012},
  volume={139 2},
  pages={599-604}
}
ETHNOPHARMACOLOGICAL RELEVANCE Solanum nigrum L. (SNL), a traditional Chinese medicinal herb endowed with diuretic, antipyretic and hepatoprotective effects, has been used as a major ingredient of folk prescriptions for anticancer treatment in China. AIM OF THE STUDY The purpose of this study was to evaluate the inhibitory effect of solamargine (SM), a major steroidal alkaloid glycoside purified from SNL, on human hepatoma SMMC-7721 cells and investigate the possible mechanism of SM… CONTINUE READING

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