Induction of apoptosis in human cancer cells by a Bacillus lipopeptide bacillomycin D.

@article{Hajare2013InductionOA,
  title={Induction of apoptosis in human cancer cells by a Bacillus lipopeptide bacillomycin D.},
  author={S. Hajare and M. Subramanian and S. Gautam and A. Sharma},
  journal={Biochimie},
  year={2013},
  volume={95 9},
  pages={
          1722-31
        }
}
A newly isolated and characterized Bacillus amyloliquefaciens strain fiply 3A has been found to produce an extracellular cyclic lipopeptide which structurally resembled bacillomycin D, earlier reported to be produced by Bacillus subtilis. The lipopeptide showed a dose dependent killing of three different human cancer cell lines viz. A549 (alveolar adenocarcinoma), A498 (renal carcinoma) and HCT-15 (colon adenocarcinoma), while not affecting the normal cell line L-132 (pulmonary epithelial cells… Expand
View on PubMed
doi.org
29 Citations
Highly Influential Citations
1
Background Citations
11
Methods Citations
1

29 Citations

Citation Type

Citation Type

Potential of Bacillus subtilis lipopeptides in anti-cancer I: induction of apoptosis and paraptosis and inhibition of autophagy in K562 cells
  • 27
Iturin A‐like lipopeptides from Bacillus subtilis trigger apoptosis, paraptosis, and autophagy in Caco‐2 cells
  • 19
Bacillomycin D-C16 triggers apoptosis of gastric cancer cells through the PI3K/Akt and FoxO3a signaling pathways
  • 4
Development of glycolipid biosurfactant for inducing apoptosis in HeLa cells
  • 10
Cytotoxic activity, DNA damage, cellular uptake, apoptosis and western blot analysis of ruthenium(II) polypyridyl complex against human lung decarcinoma A549 cell.
  • 33
Bacillomycin D effectively controls growth of Malassezia globosa by disrupting the cell membrane
Effect of cell culture models on the evaluation of anticancer activity and mechanism analysis of the potential bioactive compound, iturin A, produced by Bacillus subtilis.
  • 2
Photoinduced ROS regulation of apoptosis and mechanism studies of iridium(III) complex against SGC-7901 cells
  • 7
  • PDF
Marine bacterial surfactin CS30-2 induced necrosis-like cell death in Huh7.5 liver cancer cells
Biological activity of lipopeptides from Bacillus
  • 73
...
1
2
3
...

References

SHOWING 1-10 OF 39 REFERENCES
Effect of themicrobial lipopeptide on tumor cell lines: apoptosis induced by disturbing the fatty acid composition of cell membrane
  • 23
  • PDF
Induction of apoptosis in human leukemia K562 cells by cyclic lipopeptide from Bacillus subtilis natto T-2
  • 55
  • Highly Influential
Scutellaria litwinowii Induces Apoptosis Through Both Extrinsic and Intrinsic Apoptotic Pathways in Human Promyelocytic Leukemia Cells
  • 14
Involvement of caspase‐3‐like protein in rapid cell death of Xanthomonas
  • 51
Surfactin Induces Apoptosis and G2/M Arrest in Human Breast Cancer MCF-7 Cells Through Cell Cycle Factor Regulation
  • 54
Surfactin from Bacillus subtilis displays anti‐proliferative effect via apoptosis induction, cell cycle arrest and survival signaling suppression
  • 116
  • PDF
Mitochondrial dysfunction is an essential step for killing of non-small cell lung carcinomas resistant to conventional treatment
  • 72
  • PDF
CLP induces apoptosis in human leukemia K562 cells through Ca(2+) regulating extracellular-related protein kinase ERK activation.
  • 21
  • PDF
Natural functions of lipopeptides from Bacillus and Pseudomonas: more than surfactants and antibiotics.
  • 659
  • PDF
Surfactin induces apoptosis in human breast cancer MCF-7 cells through a ROS/JNK-mediated mitochondrial/caspase pathway.
  • 120
...
1
2
3
4
...