Induction of apoptosis in human cancer cells by a Bacillus lipopeptide bacillomycin D.

@article{Hajare2013InductionOA,
  title={Induction of apoptosis in human cancer cells by a Bacillus lipopeptide bacillomycin D.},
  author={S. Hajare and M. Subramanian and S. Gautam and A. Sharma},
  journal={Biochimie},
  year={2013},
  volume={95 9},
  pages={
          1722-31
        }
}
A newly isolated and characterized Bacillus amyloliquefaciens strain fiply 3A has been found to produce an extracellular cyclic lipopeptide which structurally resembled bacillomycin D, earlier reported to be produced by Bacillus subtilis. The lipopeptide showed a dose dependent killing of three different human cancer cell lines viz. A549 (alveolar adenocarcinoma), A498 (renal carcinoma) and HCT-15 (colon adenocarcinoma), while not affecting the normal cell line L-132 (pulmonary epithelial cells… Expand
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