Induction of apoptosis by cancer chemotherapy.

@article{Kaufmann2000InductionOA,
  title={Induction of apoptosis by cancer chemotherapy.},
  author={Scott H. Kaufmann and William C Earnshaw},
  journal={Experimental cell research},
  year={2000},
  volume={256 1},
  pages={
          42-9
        }
}
Studies performed over the past five years have demonstrated that there are two major cell-intrinsic pathways for inducing apoptosis, one that begins with ligation of cell surface death receptors and another that involves mitochondrial release of cytochrome c. Several reports have suggested that anticancer drugs kill susceptible cells by inducing expression of death receptor ligands, especially Fas ligand (FasL). Other reports have indicated that chemotherapeutic agents trigger apoptosis by… CONTINUE READING

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