Induction of antioxidant enzymes by dexamethasone in the adult rat lung.

@article{Jos1997InductionOA,
  title={Induction of antioxidant enzymes by dexamethasone in the adult rat lung.},
  author={H J Jos{\'e} and S G Berenice and V R Cecilia},
  journal={Life sciences},
  year={1997},
  volume={60 23},
  pages={2059-67}
}
Catalase, glutathione peroxidase and superoxide dismutase enzymes were determined after administering dexamethasone. Catalase increased its activity over six times (0.388 U/mg DNA) the normal rate, while glutathione peroxidase caused 3 times an increase one hour after dexamethasone injection. Superoxide dismutase increased gradually during the 3 hour treatment. The antioxidant enzyme activities decreased to basal values in the presence of protein synthesis (Cycloheximide) and RNA synthesis… CONTINUE READING