Induction of antigen-specific systemic and mucosal immune responses by feeding animals transgenic plants expressing the antigen.

@article{Bae2003InductionOA,
  title={Induction of antigen-specific systemic and mucosal immune responses by feeding animals transgenic plants expressing the antigen.},
  author={Jong-Lye Bae and Jong-Gul Lee and Tae-Jin Kang and Hyon-Seok Jang and Yong-Suk Jang and Moon-sik Yang},
  journal={Vaccine},
  year={2003},
  volume={21 25-26},
  pages={4052-8}
}
A report from that the presence of lactogenic immunity in pigs protected suckling piglets from porcine epidemic diarrhea virus (PEDV) infection suggested that inducing mucosal immune responses in lactating pigs is an effective way of protecting swine from PEDV infection. In this study, we developed transgenic tobacco plants that express the antigen protein corresponding to the neutralizing epitope of PEDV spike protein, and tested whether feeding the plants to pigs induced an effective immune… CONTINUE READING
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