Induction of anti-self-immunity to cure cancer

  title={Induction of anti-self-immunity to cure cancer},
  author={N. K. Nanda and Eli E. Sercarz},
A quiet but profound revolution in theoretical framework, a paradigm shift, now has infused the consideration of therapies in autoimmune diseases and cancers, as exem-It is becoming accepted that a large set of antigenic determinants of the self have not induced self-tolerance (reviewed by Sercarz et al., 1993) and that these peptide determinants furnish target structures for autoimmune attack (reviewed by Lanzavecchia, 1995) and could provide potential targets for immune responses directed… CONTINUE READING


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Breast and ovarian cancer - specific cytotoxic T lymphocytes recognize the same HER 2 / neuderived pep tide

  • G. E. Peoples, P. S. Goedegebuure, R. Smith, D. C. Linehan, T. J. Eberlein
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