Induction of an oncofetal marker protein upon X-radiation of rat mammary glands.

Fifty-day-old female Sprague--Dawley rats were given carcinogenic and sub-carcinogenic doses of X-radiation to the mammary glands to evaluate the induction of a 60-kDa oncofetal protein (OFP-60). This protein has previously been shown to be produced in the target organ and released to circulation during chemical carcinogenesis and tumorigenesis. In a time… (More)