Induction of an antibody response in mice against human papillomavirus (HPV) type 16 after immunization with HPV recombinant Salmonella strains

@article{Krul1996InductionOA,
  title={Induction of an antibody response in mice against human papillomavirus (HPV) type 16 after immunization with HPV recombinant Salmonella strains},
  author={Mark R L Krul and Edwin Tijhaar and John A. F. W. Kleijne and Anton M. van Loon and Mirjam G. Nievers and Hans G. Schipper and Liesbeth Geerse and M. Van der Kolk and Peter A. Steerenberg and Frits R. Mooi and Willem den Otter},
  journal={Cancer Immunology, Immunotherapy},
  year={1996},
  volume={43},
  pages={44-48}
}
 Human papillomaviruses (HPV) are present in approximately 95% of all cervical carcinomas and the HPV E6 and E7 genes are continuously expressed in these lesions. There is also circumstantial evidence that often natural immunity against HPV is generated and that this is of influence on HPV-induced lesions. Stimulation of the immune system by proper… CONTINUE READING