Induction of alveolar type II cell differentiation in fetal tracheal epithelium by grafted distal lung mesenchyme.

@article{Shannon1994InductionOA,
  title={Induction of alveolar type II cell differentiation in fetal tracheal epithelium by grafted distal lung mesenchyme.},
  author={John M. Shannon},
  journal={Developmental biology},
  year={1994},
  volume={166 2},
  pages={600-14}
}
Normal branching morphogenesis and cytodifferention of the lung require a specific interaction between the epithelial rudiment and pulmonary mesenchyme. Previous studies in the mouse have shown glandular stage pulmonary mesenchyme can elicit a lung-like pattern of branching morphogenesis when grafted onto tracheal epithelium of the same age that has been denuded of its own mesenchyme. We have examined whether are not this pattern of branching is accompanied by changes in epithelial… CONTINUE READING
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