Induction of acute phase protein by recombinant human interleukin-6 (IL-6) in calves.

@article{Nakajima1993InductionOA,
  title={Induction of acute phase protein by recombinant human interleukin-6 (IL-6) in calves.},
  author={Yukiko Nakajima and E Momotani and Takehiko Murakami and Yoshiharu Ishikawa and Masami Morimatsu and Masayuki Saito and Hideki Suzuki and Kiyotaka Yasukawa},
  journal={Veterinary immunology and immunopathology},
  year={1993},
  volume={35 3-4},
  pages={385-91}
}
Interleukin-6 (IL-6) is a major inducer of acute phase proteins in human and murine species. However, the effects of IL-6 have not yet been investigated in cattle. Following continuous infusion of recombinant human IL-6, serum concentrations of bovine haptoglobin and fibrinogen increased in a manner similar to those in cattle with acute phase reaction. In… CONTINUE READING