Induction of Trypanosoma cruzi metacyclogenesis in the gut of the hematophagous insect vector, Rhodnius prolixus, by hemoglobin and peptides carrying alpha D-globin sequences.

@article{Garcia1995InductionOT,
  title={Induction of Trypanosoma cruzi metacyclogenesis in the gut of the hematophagous insect vector, Rhodnius prolixus, by hemoglobin and peptides carrying alpha D-globin sequences.},
  author={El{\'o}i de Souza Garcia and Marcelo Salabert Gonzalez and P C de Azambuja and Francisco E. Baralle and D Fraidenraich and Hector Norberto Torres and Mirtha M. Flawi{\'a}},
  journal={Experimental parasitology},
  year={1995},
  volume={81 3},
  pages={255-61}
}
Trypanosoma cruzi, a protozoan responsible for the American trypanosomiasis (Chagas disease), multiplies and differentiates in the gut of triatomine insect vectors. The effects of hemoglobin and synthetic peptides carrying alpha D-globin fragments on both the growth and the transformation of T. cruzi epimastigotes (noninfective) into metacyclic trypmastigotes (infective forms) were studied. This differentiation in the insect's gut is expressed when hemoglobin and synthetic peptides… CONTINUE READING
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