Induction of TNF-α Production by Metal Complexes of γ-Globulin Fraction Proteins and Copper and Zinc Cations

@article{Cheknev2013InductionOT,
  title={Induction of TNF-α Production by Metal Complexes of γ-Globulin Fraction Proteins and Copper and Zinc Cations},
  author={Sergei B. Cheknev and Irina E. Efremova and Maria A. Apresova and A. A. Babajantz},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2013},
  volume={154},
  pages={758-761}
}
Plasma γ-globulin fraction proteins, copper and zinc cations, and metal complexes of these cations and human serum γ-globulin induce the production of TNF-α by human blood cells. The protein modified by zinc cations is by 1.4-1.7 times more potent (p<0.001-0.01) than control γ-globulin in inducing the production of TNF-α, while metal complex formed by γ-globulin and copper is by 1.9-2.2 times more potent that the control protein (p<0.001). Under conditions of experimental induction, TNF-α is… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 10 references

Bull. Exp. Biol. Med

  • S B Cheknev, I E Efremova, L S Piskovskaya
  • Bull. Exp. Biol. Med
  • 2013

Med. Immunol

  • S B Cheknev, I E Efremova, A S Mezdrokhina, A A Babayants
  • Med. Immunol
  • 2012

Immunol. Zh

  • E N Yushkovets, I E Efremova, A A Babajantz, S B Cheknev, Ros
  • Immunol. Zh
  • 2010

Curr. Opin. Microbiol

  • E Bartee, M R Mohamed, G Mcfadden
  • Curr. Opin. Microbiol
  • 2008

Biol

  • T S Nepomnyashchikh, D V Antonets, I P Gileva, S N Shchelkunov, Uspekhi Sovrem
  • Biol
  • 2007

Biogerontology

  • S Vasto, E Mocchegiani, G Candore
  • Biogerontology
  • 2006

Am. J. Hum. Biol

  • K Z Long, N Nanthakumar
  • Am. J. Hum. Biol
  • 2004

J. Nutr

  • Z L Huang, M L Failla
  • J. Nutr
  • 2000

Immunobiology

  • P Lenz, J E Gessner, C Sautes, R E Schmidt
  • Immunobiology
  • 1996

J. Exp. Med

  • M C Cuturi, I Anegon, F Sherman
  • J. Exp. Med
  • 1989

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