Induction of SIV p27-specific multifunctional T cells in the gut following prime-boost immunization with Clostridium perfringens and adenovirus vaccines expressing SIV p27.

@article{Helmus2010InductionOS,
  title={Induction of SIV p27-specific multifunctional T cells in the gut following prime-boost immunization with Clostridium perfringens and adenovirus vaccines expressing SIV p27.},
  author={Ruth Anne Helmus and Poonam Poonam and Lori Caruso and Phalguni Gupta and Yue Chen},
  journal={Current HIV research},
  year={2010},
  volume={8 2},
  pages={101-12}
}
A vaccine-induced cellular immune response to simian immunodeficiency virus (SIV) in the gut mucosal tissue may prevent the establishment or severity of new SIV infection. An oral Clostridium perfringens expressing SIV p27 (Cp-p27) vaccine that delivers SIV p27 to the gut was evaluated for its ability to prime multifunctional cellular immunity in the gut… CONTINUE READING