Induction of Neurasthenic Musculoskeletal Pain Syndrome by Selective Sleep Stage Deprivation

  title={Induction of Neurasthenic Musculoskeletal Pain Syndrome by Selective Sleep Stage Deprivation},
  author={Harvey Moldofsky and P Scarisbrick},
  journal={Psychosomatic Medicine},
&NA; Two groups of young, healthy, nonathletic volunteers were subjected to selective sleep stage deprivation. Six subjects were deprived of stage 4 sleep and seven subjects of REM sleep. The stage 4 deprived group reported more musculoskeletal symptoms during the deprivation condition than did the REM deprived group. The stage 4 deprived group also showed a significant increase in muscle tenderness between the baseline and deprivation conditions and an altered pattern of overnight change in… 
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