Induction of NANOG expression by targeting promoter sequence with small activating RNA antagonizes retinoic acid-induced differentiation

Abstract

RNAa (RNA activation) is a mechanism by which small dsRNA (double-stranded RNA), termed saRNA (small activating RNA), target promoter sequences to induce gene expression. This technique represents a novel approach to gene overexpression without the use of exogenous DNA. In the present study, we investigated whether RNAa can modulate expression of the… (More)
DOI: 10.1042/BJ20111491

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@inproceedings{Wang2012InductionON, title={Induction of NANOG expression by targeting promoter sequence with small activating RNA antagonizes retinoic acid-induced differentiation}, author={Xiaoling Wang and Ji Wang and Vera Huang and Robert F. Place and Long-Cheng Li}, booktitle={The Biochemical journal}, year={2012} }