Induction of Mendelian and non-Mendelian streptomycin resistant mutants during the synchronous cell cycle of Chlamydomonas reinhardtii

@article{Lee1973InductionOM,
  title={Induction of Mendelian and non-Mendelian streptomycin resistant mutants during the synchronous cell cycle of Chlamydomonas reinhardtii},
  author={Robert W. Lee and Raymond C. F. Jones},
  journal={Molecular and General Genetics MGG},
  year={1973},
  volume={121},
  pages={99-108}
}
SummaryIn synchronized cultures of Chlamydomonas reinhardtii N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) was found to selectively mutate replicating forms of nuclear DNA. This conclusion was based on the 15- to 30-fold increase in the recovery of MNNG induced Mendelian streptomycin resistant mutants (sr-1) which was correlated with mutagenesis during the period of nuclear DNA replication. No concomitant increase in the recovery of non-Mendelian streptomycin resistant mutants (sr-2) occurred… CONTINUE READING

Citations

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Molecular techniques to interrogate and edit the Chlamydomonas nuclear genome.

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HIGHLY INFLUENCED

Lethal and mutagenic effects of nitrosoguanidine on synchronizedChlamydomonas

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