Induction of M2 Polarization in Primary Culture Liver Macrophages from Rats with Acute Pancreatitis

@inproceedings{Xu2014InductionOM,
  title={Induction of M2 Polarization in Primary Culture Liver Macrophages from Rats with Acute Pancreatitis},
  author={Lixia Xu and Fen Yang and Rong Jing Lin and Chaoqun Han and Jun Liu and Zhen Ding and Juan Sastre},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND AND AIMS Systemic inflammatory response syndrome (SIRS), a major process of severe acute pancreatitis (SAP), usually occurs after various activated proinflammatory cytokines, which are produced by macrophages such as liver macrophages. Macrophages can secrete not only proinflammatory mediators but also inhibitory inflammatory cytokines such as IL-10, leading to two different functional states defined as "polarization". The main purpose of this study was to demonstrate the… CONTINUE READING
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