Induction of IgM and IgM-rheumatoid factor synthesis in vitro by indomethacin

Abstract

Indomethacin, which is thought to exert its therapeutic effect by inhibiting the synthesis of PGE2, is a commonly used first-line agent in the treatment of rheumatoid arthritis (RA). However, the effect of this drug on the humoral immune response in RA remains unclear. In this study, modulation of the in vitro synthesis of IgM and IgM-rheumatoid factor (RF… (More)
DOI: 10.1007/BF02274885

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@article{Hassan1991InductionOI, title={Induction of IgM and IgM-rheumatoid factor synthesis in vitro by indomethacin}, author={Jaythoon Hassan and Ashley M. Whelan and Barry Bresnihan and Cliona Feighery}, journal={Rheumatology International}, year={1991}, volume={10}, pages={235-239} }